Product Description
Hydrocortisone Vial 100mg is a medication containing hydrocortisone, a potent corticosteroid hormone. This vial contains 100mg of hydrocortisone in a powdered form, which needs to be reconstituted with a sterile solution before administration.
Uses:
Hydrocortisone is a versatile medication used to treat a wide range of conditions, including:
- Endocrine Disorders: It's used to treat primary or secondary adrenocortical insufficiency, where the adrenal glands don't produce enough cortisol, a crucial hormone.
- Collagen Diseases: It's used to manage conditions like systemic lupus erythematosus, an autoimmune disorder that affects various organs.
- Dermatological Diseases: It's used to treat severe skin conditions like erythema multiforme (Stevens-Johnson syndrome), a serious skin reaction.
- Allergic States: It's used to treat severe allergic reactions, including anaphylaxis, and to manage conditions like bronchial asthma.
- Gastrointestinal Diseases: It's used to manage inflammatory bowel diseases like ulcerative colitis and Crohn's disease.
- Respiratory Diseases: It's used to treat aspiration of gastric contents, where stomach contents enter the lungs.
- Medical Emergencies: It's used to treat shock secondary to adrenocortical insufficiency or shock unresponsive to conventional therapy, where adrenocortical insufficiency may be present.
Dosage and Administration:
Hydrocortisone Vial 100mg is typically administered intravenously, either as a slow injection or as an infusion. The dosage varies depending on the condition being treated and the patient's response. The initial emergency dose is usually 100mg to 500mg, administered intravenously over 1 to 10 minutes. This dose may be repeated every 2, 4, or 6 hours as needed.
Important Precautions:
- Hypersensitivity: Hydrocortisone is contraindicated in patients with known hypersensitivity to the drug or any of its excipients.
- Systemic Fungal Infections: It's contraindicated in patients with systemic fungal infections unless specific anti-infective therapy is employed.
- Live Vaccines: Administration of live or live, attenuated vaccines is contraindicated in patients receiving immunosuppressive doses of corticosteroids.
- Long-Term Use: Prolonged use of hydrocortisone can lead to adrenal cortical atrophy, a condition where the adrenal glands shrink. This can cause adrenal insufficiency, a serious condition where the body doesn't produce enough cortisol.
- Withdrawal: Abrupt withdrawal of hydrocortisone after prolonged use can also cause adrenal insufficiency. Therefore, the dosage should be gradually reduced under medical supervision.
- Infections: Corticosteroids can suppress the immune system, making patients more susceptible to infections.
- Peptic Ulceration: High-dose, short-term corticosteroid therapy can increase the risk of peptic ulceration. Prophylactic antacid therapy may be indicated.
- Stress: Patients subjected to severe stress following corticosteroid therapy should be observed closely for signs and symptoms of adrenocortical insufficiency.
- Liver Disease: Patients with liver disease may experience an increased effect of hydrocortisone. Reduced dosing may be considered.
- Elderly Patients: Elderly patients may be more sensitive to the side effects of corticosteroids. Close clinical supervision is required.
- Pediatric Population: The dose may be reduced for infants and children, but it's governed more by the severity of the condition and response of the patient than by age or body weight.
Side Effects:
Common side effects of hydrocortisone include:
- Fluid Retention: This can lead to swelling in the legs and feet.
- Weight Gain: This is due to fluid retention and increased appetite.
- Mood Changes: This can include irritability, anxiety, and depression.
- Insomnia: Difficulty sleeping.
- Increased Blood Sugar: This can worsen diabetes.
- High Blood Pressure: This is uncommon but possible.
- Peptic Ulceration: This is a risk with high-dose, short-term therapy.
More serious side effects are less common but can include:
- Adrenal Insufficiency: This can occur if hydrocortisone is stopped abruptly after prolonged use.
- Osteoporosis: This is a weakening of the bones.
- Cataracts: Clouding of the lens of the eye.
- Glaucoma: Increased pressure in the eye.
- Immunosuppression: This can make patients more susceptible to infections.
Important Note:
This information is for general knowledge only and should not be considered medical advice. Always consult with your doctor or pharmacist for specific dosage instructions, potential risks, and any other questions you may have regarding Hydrocortisone Vial 100mg.
