Product Description
Ketorolac Ampule 30mg/ml is a concentrated solution of ketorolac trometamol, a nonsteroidal anti-inflammatory drug (NSAID), used for short-term management of moderate to severe acute post-operative pain in adults. It's typically administered intravenously or intramuscularly, carefully monitored by healthcare professionals.
Product Description:
This product comes in a single-dose ampule containing 1ml of a sterile solution of ketorolac trometamol. The concentration is 30mg/ml, meaning each ampule provides a total of 30mg of ketorolac trometamol.
Indications:
Ketorolac Ampule is indicated for the short-term management of moderate to severe acute post-operative pain. It's important to note that treatment should only be initiated in a hospital setting, and the maximum duration of treatment is two days.
Dosage Recommendation:
Dosage is highly individualized and depends on the patient's specific condition, age, weight, and response to treatment. It's crucial to follow the dosage instructions provided by your doctor carefully.
- Initial Dose: The recommended initial dose is 10mg, followed by 10 to 30mg every four to six hours as needed.
- Maximum Daily Dose: A total daily dose of 90mg for non-elderly patients and 60mg for the elderly, renally impaired patients, and patients less than 50kg should not be exceeded.
- Opioid Concomitant Use: Opioid analgesics (e.g., morphine, pethidine) may be used concomitantly and may be required for optimal analgesic effect in the early post-operative period when pain is most severe.
Precautions:
Ketorolac Ampule should be used with caution in patients with:
- Gastrointestinal Issues: Ketorolac can cause gastrointestinal bleeding, ulceration, or perforation, which can be fatal. The risk is higher with increasing doses and in patients with a history of ulcers.
- Cardiovascular Risk: NSAIDs, including ketorolac, may increase the risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke.
- Renal Impairment: Ketorolac is contraindicated in patients with moderate to severe renal impairment. Dosage should be reduced in patients with lesser impairment.
- Hypersensitivity: Ketorolac is contraindicated in patients with previously demonstrated hypersensitivity to ketorolac, any of its excipients, or other NSAIDs.
- Pregnancy and Breastfeeding: Ketorolac is contraindicated in pregnancy, labor, delivery, or lactation.
Adverse Reactions:
Common side effects of ketorolac include:
- Gastrointestinal: Gastrointestinal bleeding, ulceration, or perforation, nausea, vomiting, abdominal pain, diarrhea.
- Cardiovascular: Heart attack, stroke, hypertension.
- Central Nervous System: Headache, dizziness, drowsiness, confusion.
- Hematologic: Inhibition of platelet aggregation, increased risk of bleeding.
Serious side effects are less common but can include:
- Anaphylaxis: Severe allergic reaction.
- Seizures: Increased risk in patients with a history of seizures.
- Renal Failure: Especially in patients with pre-existing renal impairment.
Important Note:
This information is for general knowledge and should not be considered medical advice. Always consult with your doctor or pharmacist for specific dosage instructions, potential risks, and any other questions you may have regarding Ketorolac Ampule.
