Product Description
Nicardipine Ampule 1mg/ml (10mg/10ml) is a concentrated solution of nicardipine hydrochloride, a calcium channel blocker, used for the short-term treatment of acute, life-threatening hypertension in adults. It's typically administered intravenously as a continuous infusion, carefully monitored by healthcare professionals.
Product Description:
This product comes in a single-dose ampule containing 10ml of a sterile solution of nicardipine hydrochloride. The concentration is 1mg/ml, meaning each ampule provides a total of 10mg of nicardipine hydrochloride.
Indications:
Nicardipine Ampule is indicated for the treatment of:
- Malignant arterial hypertension/hypertensive encephalopathy: This is a severe form of hypertension that can damage the brain.
- Aortic dissection: This is a tear in the wall of the aorta, the main artery that carries blood from the heart.
- Severe pre-eclampsia: This is a serious condition that can occur during pregnancy, characterized by high blood pressure and other symptoms.
- Post-operative hypertension: High blood pressure that occurs after surgery.
Dosage Recommendation:
Dosage is highly individualized and depends on the patient's specific condition, age, weight, and response to treatment. It's crucial to follow the dosage instructions provided by your doctor carefully.
- Initial Dose: The initial dose is typically 3-5mg/hour, administered intravenously as a continuous infusion.
- Maintenance Dose: The dose is adjusted to maintain the desired blood pressure, usually between 2 and 4mg/hour.
- Titration: The dose should be adjusted carefully, increasing or decreasing by increments of 0.5mg or 1mg every 15 minutes, depending on the patient's response.
Precautions:
Nicardipine Ampule should be used with caution in patients with:
- Heart problems: Nicardipine can worsen heart problems, especially in patients with pre-existing conditions like congestive heart failure or unstable angina.
- Liver disease: Nicardipine can worsen liver problems.
- Kidney disease: Nicardipine can worsen kidney problems.
- Pregnancy: Nicardipine can cause harm to the fetus.
- Breastfeeding: Nicardipine can pass into breast milk and may harm the baby.
Adverse Reactions:
Common side effects of nicardipine include:
- Hypotension: Low blood pressure.
- Headache: Pain in the head.
- Flushing: Redness of the skin.
- Dizziness: Feeling lightheaded.
- Nausea: Feeling sick to the stomach.
- Edema: Swelling.
Serious side effects are less common but can include:
- Cardiac arrhythmias: Abnormal heart rhythms.
- Hypotension after abrupt discontinuation: Sudden drop in blood pressure when the medication is stopped abruptly.
- Severe allergic reactions (anaphylaxis): Life-threatening allergic reaction.
Important Note:
This information is for general knowledge and should not be considered medical advice. Always consult with your doctor or pharmacist for specific dosage instructions, potential risks, and any other questions you may have regarding Nicardipine Ampule.
