Product Description
Paracetamol + Tramadol Tablet 325mg/37.5mg is a combination medication used to treat moderate to severe pain. It contains two active ingredients: paracetamol (also known as acetaminophen) and tramadol hydrochloride.
How it Works:
- Paracetamol is a non-opioid pain reliever that works by reducing fever and pain signals in the brain.
- Tramadol hydrochloride is an opioid pain reliever that works by binding to opioid receptors in the brain and spinal cord, reducing pain perception.
Uses:
This medication is prescribed for the management of moderate to severe pain when a combination of paracetamol and tramadol is deemed necessary by a doctor. It is typically used for pain that is not adequately relieved by paracetamol alone.
Important Information:
- Prescription Only: This medication is available only with a prescription from a qualified healthcare professional.
- Dosage: The recommended dose varies based on the individual's pain level and medical history. It is crucial to follow your doctor's instructions carefully.
- Maximum Dosage: The maximum daily dose is 8 tablets (equivalent to 300mg tramadol and 2600mg paracetamol) per day, with a minimum interval of 6 hours between doses.
- Duration of Use: This medication should only be used for as long as strictly necessary. Prolonged use can lead to dependence and addiction.
- Not Suitable for Children: This medication is not recommended for children under 12 years old.
- Elderly Patients: Dosage adjustments may be necessary for elderly patients over 75 years old due to slower elimination of tramadol.
- Renal and Hepatic Impairment: This medication is not recommended for patients with severe renal insufficiency (creatinine clearance < 10 ml/min) or severe hepatic impairment.
Potential Side Effects:
Common side effects include:
- Nausea
- Vomiting
- Dizziness
- Drowsiness
- Constipation
- Headache
- Dry mouth
- Sweating
Serious side effects can occur, including:
- Serotonin Syndrome: This is a potentially life-threatening condition that can occur when taking tramadol with other serotonergic drugs (such as SSRIs, SNRIs, MAOIs, and tricyclic antidepressants). Symptoms include mental status changes, autonomic instability, neuromuscular abnormalities, and gastrointestinal symptoms.
- Respiratory Depression: Tramadol can suppress breathing, especially when taken in high doses or with other medications that depress the central nervous system.
- Addiction and Dependence: Prolonged use of tramadol can lead to dependence and addiction.
- Seizures: Tramadol can lower the seizure threshold, increasing the risk of seizures in people with epilepsy or those taking medications that lower the seizure threshold.
- Liver Problems: Paracetamol overdose can cause liver damage.
Important Precautions:
- Alcohol: Avoid alcohol consumption while taking this medication, as it can increase the risk of drowsiness and respiratory depression.
- Other Medications: Inform your doctor about all medications you are taking, including over-the-counter medications, herbal supplements, and vitamins.
- Pregnancy and Breastfeeding: This medication is not recommended during pregnancy or breastfeeding.
- Driving and Operating Machinery: This medication can cause drowsiness and dizziness, so avoid driving or operating machinery until you know how it affects you.
Disclaimer:
This information is not a substitute for professional medical advice. Always consult with your doctor or pharmacist before taking any medication.
