Product Description
Prednisolone syrup containing 15mg of prednisolone in each 5ml is a common medication used to treat a variety of inflammatory and autoimmune conditions, particularly in children and individuals who have difficulty swallowing tablets.
What is Prednisolone?
Prednisolone is a corticosteroid, a type of medication that reduces inflammation and suppresses the immune system. It is a synthetic version of naturally occurring hormones produced by the adrenal glands. Prednisolone works by reducing inflammation and suppressing the immune system's response to various stimuli.
Uses of Prednisolone Syrup:
Prednisolone syrup is indicated for a wide range of conditions, including:
- Endocrine Disorders: Primary or secondary adrenocortical insufficiency, congenital adrenal hyperplasia, hypercalcemia associated with cancer, and nonsuppurative thyroiditis.
- Rheumatic Disorders: As adjunctive therapy for short-term administration in conditions like psoriatic arthritis, rheumatoid arthritis, ankylosing spondylitis, bursitis, tenosynovitis, gouty arthritis, osteoarthritis, and epicondylitis.
- Collagen Diseases: During exacerbations or as maintenance therapy in systemic lupus erythematosus, systemic dermatomyositis, and acute rheumatic carditis.
- Dermatologic Diseases: Pemphigus, bullous dermatitis herpetiformis, severe erythema multiforme, exfoliative dermatitis, mycosis fungoides, severe psoriasis, and severe seborrheic dermatitis.
- Allergic States: Control of severe or incapacitating allergic conditions like seasonal or perennial allergic rhinitis, bronchial asthma, contact dermatitis, atopic dermatitis, serum sickness, and drug hypersensitivity reactions.
- Ophthalmic Diseases: Severe acute and chronic allergic and inflammatory processes involving the eye, such as allergic corneal marginal ulcers, herpes zoster ophthalmicus, anterior segment inflammation, uveitis, choroiditis, sympathetic ophthalmia, allergic conjunctivitis, keratitis, chorioretinitis, optic neuritis, iritis, and iridocyclitis.
- Respiratory Diseases: Symptomatic sarcoidosis, Loeffler's syndrome, berylliosis, fulminating or disseminated pulmonary tuberculosis (when used concurrently with appropriate antituberculous chemotherapy), and aspiration pneumonitis.
- Hematologic Disorders: Idiopathic thrombocytopenic purpura, secondary thrombocytopenia, acquired (autoimmune) hemolytic anemia, erythroblastopenia, and congenital (erythroid) hypoplastic anemia.
- Neoplastic Diseases: For palliative management of leukemias and lymphomas in adults, and acute leukemia in childhood.
- Edematous States: To induce diuresis or remission of proteinuria in nephrotic syndrome without uremia.
- Gastrointestinal Diseases: To manage ulcerative colitis and regional enteritis.
- Nervous System: Acute exacerbations of multiple sclerosis.
- Miscellaneous: Tuberculous meningitis with subarachnoid block, trichinosis with neurologic or myocardial involvement.
Important Considerations:
- Contraindications: Prednisolone syrup is contraindicated in systemic fungal infections and known hypersensitivity to the components.
- Warnings:
- Prednisolone can mask signs of infection, and new infections may appear during its use.
- Prolonged use can lead to posterior subcapsular cataracts, glaucoma, and secondary ocular infections.
- It can cause elevation of blood pressure, salt and water retention, and increased potassium excretion.
- Live or live, attenuated vaccines are contraindicated in patients receiving immunosuppressive doses of prednisolone.
- It should be used cautiously in patients with active tuberculosis, latent tuberculosis, or tuberculin reactivity.
- Prednisolone can increase susceptibility to infections, particularly chickenpox and measles.
- Precautions:
- Drug-induced secondary adrenocortical insufficiency may occur.
- Prednisolone has an enhanced effect in patients with hypothyroidism and cirrhosis.
- It should be used cautiously in patients with ocular herpes simplex.
- The lowest possible dose should be used, and dosage reduction should be gradual.
- Psychic derangements may occur, ranging from euphoria to psychotic manifestations.
- Aspirin should be used cautiously in conjunction with prednisolone in hypoprothrombinemia.
- Prednisolone should be used with caution in nonspecific ulcerative colitis, diverticulitis, fresh intestinal anastomoses, active or latent peptic ulcer, renal insufficiency, hypertension, osteoporosis, and myasthenia gravis.
- Growth and development of infants and children on prolonged prednisolone therapy should be carefully observed.
- Dosage and Administration:
- The dosage of prednisolone syrup varies depending on the condition being treated and the individual's response to the medication.
- It is typically taken by mouth, usually with food or milk to prevent stomach upset.
- The dosage and duration of treatment are determined by a doctor based on the specific needs of the patient.
- Side Effects:
- Prednisolone can cause a variety of side effects, some of which can be serious. Common side effects include nausea, vomiting, loss of appetite, heartburn, trouble sleeping, increased sweating, and acne.
- More serious side effects can include muscle pain/cramps, irregular heartbeat, weakness, swelling, unusual weight gain, signs of infection, vision problems, symptoms of stomach/intestinal bleeding, mental/mood changes, slow wound healing, thinning skin, bone pain, menstrual period changes, puffy face, seizures, easy bruising/bleeding, red/purple spots on the skin, and high blood sugar.
- A very serious allergic reaction to prednisolone is rare, but if you notice any symptoms such as rash, itching/swelling, severe dizziness, or trouble breathing, seek medical help immediately.
- Drug Interactions:
- Prednisolone can interact with other medications, including opioids, alcohol, and other medications. Inform your doctor about all the medications you are taking, including over-the-counter medications and herbal supplements.
Important Note:
This information is not a substitute for professional medical advice. Always consult with your doctor or pharmacist before taking any medication.
