Product Description
Isoxsuprine Ampule 5mg/ml is a concentrated solution of isoxsuprine hydrochloride, a medication primarily used to treat circulatory problems and uterine hypermotility. It's a beta-adrenergic agonist, meaning it stimulates beta-adrenergic receptors, leading to relaxation of smooth muscles in blood vessels and the uterus.
How it Works:
- Vasodilation: Isoxsuprine primarily acts on the smooth muscles of blood vessels, particularly those in the cerebral vessels and deeper vessels of the limbs. This vasodilating action helps improve blood flow to these areas, potentially relieving symptoms of circulatory problems.
- Uterine Relaxation: In higher doses, isoxsuprine can relax the smooth muscles of the uterus. This effect has been used to treat uterine hypermotility and potentially delay premature labor.
- Blood Viscosity: Isoxsuprine is also believed to have a positive effect on blood viscosity, which can further improve blood flow.
Uses:
Isoxsuprine is commonly used to treat:
- Circulatory Disturbances: This includes conditions like arteriosclerosis obliterans, thromboangiitis obliterans (Buerger's disease), Raynaud's phenomenon, and cerebrovascular insufficiency.
- Uterine Hypermotility: This includes conditions like threatened premature labor.
Dosage and Administration:
Dosage is highly individualized and depends on the patient's specific condition, age, weight, and response to treatment. It's crucial to follow the dosage instructions provided by your doctor carefully.
- Typical Dose: The typical dose is 10mg (2ml of the 5mg/ml solution) administered intravenously or intramuscularly.
- Frequency: The frequency of administration depends on the patient's condition and the doctor's recommendation.
Precautions:
Isoxsuprine should be used with caution in patients with:
- Recent Arterial Hemorrhage: Isoxsuprine is contraindicated in patients who have recently experienced arterial bleeding.
- Heart Disease: It should be used with caution in patients with known heart disease.
- Severe Anemia: It should not be used in patients with severe anemia.
- Hypotension: Isoxsuprine should not be administered parenterally (by injection) to patients with low blood pressure.
- Tachycardia: It should not be administered parenterally to patients with a rapid heart rate.
- Premature Detachment of the Placenta: It should not be administered parenterally to patients with premature detachment of the placenta.
- Postpartum: It should not be administered parenterally immediately after childbirth.
Side Effects:
Common side effects of isoxsuprine include:
- Palpitations: A feeling of a rapid or irregular heartbeat.
- Hypotension: Low blood pressure.
- Dizziness: Feeling lightheaded.
- Increased Fetal Heart Rate: A slight increase in the baby's heart rate when administered intravenously during premature labor.
- Skin Rashes: Rarely, skin rashes have been associated with isoxsuprine use.
Important Note:
This information is for general knowledge and should not be considered medical advice. Always consult with your doctor or pharmacist for specific dosage instructions, potential risks, and any other questions you may have regarding Isoxsuprine Ampule.
