Product Description
Trimetazidine Tablet 35mg is a medication used to treat stable angina pectoris, a type of chest pain caused by reduced blood flow to the heart. It is typically used in patients whose angina is not adequately controlled or who are intolerant to first-line therapies.
How Trimetazidine Works:
The exact mechanism of action of trimetazidine is not fully understood. However, it is believed to work by:
- Inhibiting Fatty Acid Oxidation: Trimetazidine may inhibit an enzyme called 3-ketoacyl coenzyme A thiolase, which is involved in the breakdown of fatty acids for energy production. By inhibiting this enzyme, trimetazidine shifts the heart's energy source from fatty acids to glucose, which is more efficient in the presence of reduced oxygen supply. This helps to reduce the heart's oxygen demand and alleviate angina symptoms.
- Improving Energy Metabolism: Trimetazidine may also improve the heart's ability to utilize glucose as an energy source, further reducing its oxygen demand.
Uses of Trimetazidine Tablet 35mg:
- Stable Angina Pectoris: Trimetazidine is indicated for the symptomatic treatment of stable angina pectoris in patients inadequately controlled or intolerant to first-line therapies.
- Other Potential Uses: Trimetazidine has been studied for other conditions, including tinnitus (ringing in the ears), vertigo (a spinning sensation), and visual field disturbances. However, it is not currently approved for these uses in all countries.
Dosage and Administration:
- Dosage: The usual dosage of trimetazidine is 35mg taken twice daily, usually at mealtimes.
- Administration: Trimetazidine is typically taken by mouth. The tablet should be swallowed whole with a glass of water. Do not crush, break, or chew the tablet, as this may affect its release and absorption.
Important Precautions:
- Hypersensitivity: Trimetazidine is contraindicated in patients with known hypersensitivity to trimetazidine or any of its ingredients.
- Liver and Kidney Function: Trimetazidine should be used with caution in patients with impaired liver or kidney function, as it may be eliminated more slowly in these individuals.
- Parkinson's Disease: Trimetazidine may worsen symptoms of Parkinson's disease. It is important to inform your doctor if you have Parkinson's disease before starting trimetazidine.
- Drug Interactions: Trimetazidine may interact with other medications, including:
- Sedatives or Hypnotics: Trimetazidine may enhance the sedative effects of these medications.
- Strong Painkillers: Trimetazidine may increase the risk of side effects from strong painkillers.
- Antidepressants: Trimetazidine may interact with certain antidepressants, such as fluoxetine and lithium.
- Blood Pressure Medications: Trimetazidine may interact with medications to lower blood pressure.
- Parkinson's Disease Medications: Trimetazidine may interact with medications to treat Parkinson's disease.
- Anti-Epileptic Medications: Trimetazidine may interact with certain anti-epileptic medications.
- Alcohol: Alcohol should be avoided while taking trimetazidine, as it may increase the risk of side effects.
Side Effects:
Common side effects of trimetazidine include:
- Dizziness
- Headache
- Diarrhea
- Vomiting
- Indigestion
- Abdominal pain
- Feeling sick
Less common, but more serious side effects can include:
- Worsening of Parkinson's disease symptoms
- Changes in vision
- Changes in appetite
Overdose:
If you suspect an overdose, seek medical attention immediately.
Key Takeaways:
- Trimetazidine Tablet 35mg is a medication used to treat stable angina pectoris.
- It works by shifting the heart's energy source from fatty acids to glucose, reducing oxygen demand.
- It is important to be aware of potential side effects, drug interactions, and the need for careful monitoring.
- Always consult with a healthcare professional for specific medical advice.
Disclaimer: This information is for general knowledge only and should not be considered medical advice. Always consult with your doctor or pharmacist for specific dosage instructions, potential risks, and any other questions you may have regarding Trimetazidine Tablet 35mg.
